Cas Substance
Cas Substance Details
Note: All costs provided here are estimates and may vary
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If you wish to join the registration and purchase a Letter of Access, please open an account here. Once you have opened an account you will be able to submit a Letter of Access purchase request for this substance.| Endpoint Name | Estimated Cost | Executive Summary | Conclusion | |
|---|---|---|---|---|
| AcuteToxicityOral | € 1280.00 |
The acute oral median lethal dose (LD50) of
Paracetamol,when admin... |
The acute oral median lethal dose (LD50) of Parace... |
|
| AdsorptionDesorption | € 19200.00 |
The adsorption coefficient Koc in soil
and in sewage sludge parace... |
The Adsorption Coefficient of test substance parac... |
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| AutoFlammability | € 700.00 |
Paracetamol did not catch fire on being
exposed to air at room tem... |
Paracetamol did not catch fire on being exposed to... |
|
| BasicToxicokinetics |
In contrast to the adult guinea pig where
glucuronide (GLU) forms ... |
Interpretation of results (migrated information): ... |
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| BiodegradationInSoil | € 0.00 |
The PBT Profiler & EPI Suite has estimated
that Paracetamol is... |
The PBT Profiler & EPI Suite has estimated that Pa... |
|
| BiodegradationInWaterScreeningTests | € 1760.00 |
Biodegradation test was conducted following
OECD... |
In the ready biodegradability test according to OE... |
|
| BoilingPoint | € 280.00 |
The boiling point of paracetamol by the
distillation method was fo... |
The boiling point of paracetamol by the distillati... |
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| Carcinogenicity |
The
2 year study was conducted to evaluate toxic effects of contin... |
Under the conditions of these 2-year feed studies,... |
||
| Density | € 480.00 |
The bulk density of paracetamol by the mass
by volume method was found ... |
The bulk density of paracetamol by the mass by vol... |
|
| DevelopmentalToxicityTeratogenicity |
The effects of acetaminophen (APAP) was
investigated in pregnant |... |
The fetotoxicity value LOEL (Lowest observed eff... |
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| DissociationConstant | € 1280.00 |
The experimental pKa value for paracetamol
was found to be 0.000000523 ... |
The experimental pKa value for paracetamol was fou... |
|
| Flammability | € 480.00 |
From the experimental values of
flammability, paracetamol ignited ... |
From the experimental values of flammability, para... |
|
| FlashPoint | € 510.00 |
The experimental value of flash point of
paracetamol by the open cup me... |
The experimental value of flash point of paracetam... |
|
| GeneralInformation |
On the basis of physical observation and
using the sense of smell,... |
On the basis of physical observation and using the... |
||
| GeneticToxicityVitro |
Paracetamol gives negative result for DNA
damage and/or repair tes... |
Paracetamol gives negative result for DNA damage a... |
||
| GeneticToxicityVivo |
The ability of paracetamol to induce
structural chromosome aberrat... |
The ability of paracetamol to induce structural ch... |
||
| Granulometry | € 1120.00 |
The particle size distribution
(granulometry) of paracetamol by th... |
The particle size distribution (granulometry) of p... |
|
| LongTermToxicityToAquaInv |
Chronic
toxicity of Paracetamol (acetaminophen)
was ev... |
Chronic toxicity of Paracetamol (acetaminophen) wa... |
||
| LongTermToxToFish |
Chronic toxicity of acetaminophen was
evaluated using a fish (Oryz... |
Chronic toxicity of Paracetamol (acetaminophen) wa... |
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| Melting | € 280.00 |
The melting point of paracetamol by the
capillary method was found to b... |
The melting point of paracetamol by the capillary ... |
|
| OxidisingProperties | € 1120.00 |
Paracetamol was found to have mild oxidising
property since 284.4 ml of... |
Paracetamol was found to have mild oxidising prope... |
|
| Partition | € 1680.00 |
The
Solubility of paracetamol
(CAS
No.103-90-2) was ... |
The partition coefficient of test substance CAS No... |
|
| Ph | € 880.00 |
1% by volume solution of paracetamol was
found to exhibit a pH of 4.23 ... |
1% by volume solution of paracetamol was found to ... |
|
| PhototransformationInAir |
The atmospheric oxidation half-life of
Paracetamol was estimated u... |
The atmospheric oxidation half-life of Paracetamol... |
||
| RepeatedDoseToxicityInhalation |
The
subchronic repeated dose toxicity NOAEC ( No observed adv... |
The subchronic repeated dose toxicity NOAEC ( No o... |
||
| RepeatedDoseToxicityOral | € 15800.00 |
The
study was designed to evaluate the possible hepato-protective ... |
The Lowest Observed Effect Level (LOEL) of Paracet... |
|
| ShortTermToxicityToAquaInv | € 1440.00 |
Study conducted on daphnia pulex for 24 hrs
indicate the effective... |
Study conducted on daphnia pulex for 24 hrs indica... |
|
| ShortTermToxicityToFish | € 1400.00 |
The lethal concentration (LC50) value of
Paracetamol in fish (Pime... |
The lethal concentration (LC50) value of Paracetam... |
|
| SolubilityOrganic |
The experimental value of solubility of
paracetamol in ethanol at ... |
The experimental value of solubility of paracetamo... |
||
| StabilityOrganic | € 1080.00 |
Paracetamol was found to be stable in
organic solvent dichloro met... |
Paracetamol was found to be stable in organic solv... |
|
| ToxicityReproduction |
The study was conducted on 6 -8 week old
male B6C3F1 mice to test ... |
The lowest observed adverse effect level (LOAEL) v... |
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| ToxicityToAquaticAlgae | € 1360.00 |
The effect of test item paracetamol,
CAS No. 103-90-2 was studied ... |
After 72 hours of exposure to test item paracetamo... |
|
| ToxicityToMicroorganisms | € 4800.00 |
The inhibition growth concentration (IGC50)
value of Paracetamol i... |
The inhibition growth concentration (IGC50) value ... |
|
| Vapour | € 720.00 |
The vapour pressure of paracetamol was
estimated to be 0.00133322 ... |
The vapour pressure of paracetamol was estimated t... |
Are Sub-Services Required?
| Sub-Service | Estimated Rate (€100/hour) | Estimated Hours | Total Cost | |
|---|---|---|---|---|
| Translation | € 100.00/hour | 5 | € 500 | |
| Review of Studies | € 100.00/hour | 2 | € 200 | |
| Authorization | € 100.00/hour | 1 | € 100 | |
| Defense | € 100.00/hour | 2 | € 200 | |
| Interaction with Authorities | € 100.00/hour | 1 | € 100 |
Total Selected Estimated Cost:
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